Article
Radiation-induced versus endogenous DNA damage: possible effect of inducible protective responses in mitigating endogenous damage
1 Jun 2003
Abstract excerpt
Ionizing radiation (IR) causes damage to DNA that is apparently proportional to absorbed dose. The incidence of radiation-induced cancer in humans unequivocally rises with the value of absorbed doses above about 300 mGy, in a seemingly linear fashion. Extrapolation of this linear correlation down to zero-dose constitutes the linear-no-threshold (LNT) hypothesis of radiation-induced cancer incidence. The...
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