Article
A model for dose rate and duration of exposure effects in radiation carcinogenesis.
Environmental health perspectives - 1 Jul 1990
Thomas D C
Abstract excerpt
Multistage models have been used to describe various features of the incidence of cancer including the shape of the age-incidence curve; the influence of age at, duration of, and time since exposure; and the synergistic effect of exposure to multiple carcinogens. However, the models require from...
Topics
- Animals
- Cell Transformation, Neoplastic
- Cocarcinogenesis
- Cohort Studies
- DNA Damage
- Dose-Response Relationship, Radiation
- Energy Transfer
- Humans
- Likelihood Functions
- Models, Biological
- Multivariate Analysis
- Mutation
- Neoplasms, Radiation-Induced
- Oncogenes
- Poisson Distribution
- Radiation Injuries, Experimental
- Regression Analysis
- Risk