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Article

Phenotypic analysis of autosomal dominant hereditary spastic paraplegia linked to chromosome 8q.

Neurology - 13 Jul 1999

Hedera P, DiMauro S, Bonilla E, Wald J, Eldevik O P, Fink J K

Abstract excerpt

OBJECTIVE: To describe clinical, electrophysiologic, neuroimaging, and muscle biopsy features in a hereditary spastic paraplegia (HSP) kindred linked to a new HSP locus on chromosome 8q. BACKGROUND: HSP is a genetically diverse group of disorders characterized by insidiously progressive spastic weakness in the legs. We recently analyzed a Caucasian kindred with autosomal dominant HSP and identified tight linkage...

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Identifiers

PMID: 10408535
DOI: 10.1212/wnl.53.1.44

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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