Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelin converting enzyme activity in primary rat astrocytes is modulated by endothelin B receptors.

Biochemical and biophysical research communications - 22 Jul 1999

Ehrenreich H, Löffler B M, Hasselblatt M, Langen H, Oldenburg J, Subkowski T, Schilling L, Sirén A L

Abstract excerpt

Astrocytes express endothelin-1 (ET-1), ET-3, and their receptors, ET(A) and ET(B). We report here that activated astrocytes in vivo also express endothelin converting enzyme-1 (ECE-1). Higher basal ET-1 concentrations in astrocyte media from ET(B)-deficient (sl/sl) versus wildtype (+/+) rats suggested that altered ECE activity may be related to the absence of ET(B) receptors. Quantification of ECE activity in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aspartic Acid Endopeptidases
Share to Culture Media, Conditioned

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelin-1

Share to Isoelectric Point

Share to Metalloendopeptidases

Share to Rats, Mutant Strains

Share to Receptor, Endothelin B

Share to Receptors, Endothelin

Source

Identifiers

PMID: 10405338
DOI: 10.1006/bbrc.1999.0924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endothelin converting enzyme activity in primary rat astrocytes is modulated by endothelin B receptors.PMID 10405338Read ↗

Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype.Semantic proximity Read ↗

Regulation of gamma-glutamyl transpeptidase and alkaline phosphatase activities in immortalized rat brain microvessel endothelial cells.Semantic proximity Read ↗

Binding and uptake of A beta1-42 by primary human astrocytes in vitro.Semantic proximity Read ↗

Proteomic analysis of the reactive phenotype of astrocytes following endothelin-1 exposure.Semantic proximity Read ↗

Differential effects on glial activation by a direct versus an indirect thrombin inhibitor.Semantic proximity Read ↗

Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1.Semantic proximity Read ↗

Transcriptional regulation of human excitatory amino acid transporter 1 (EAAT1): cloning of the EAAT1 promoter and characterization of its basal and inducible activity in human astrocytes.Semantic proximity Read ↗

Cortical expression of endothelin receptor subtypes A and B following middle cerebral artery occlusion in rats.Semantic proximity Read ↗

Apolipoprotein E protects cultured pericytes and astrocytes from D-Abeta(1-40)-mediated cell death.Semantic proximity Read ↗

Astrocyte cultures derived from human brain tissue express angiotensinogen mRNA.Semantic proximity Read ↗

Upregulation of the glutamine transporter through transactivation mediated by cAMP/protein kinase A signals toward exacerbation of vulnerability to oxidative stress in rat neocortical astrocytes.Semantic proximity Read ↗

Contribution of thrombin-reactive brain pericytes to blood-brain barrier dysfunction in an in vivo mouse model of obesity-associated diabetes and an in vitro rat modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.