Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopy

1 Jul 1999

Abstract excerpt

Hypointense T1 lesions in multiple sclerosis patients correlate with axonal loss at autopsy and biopsy. We evaluated the chemical substrate of hypointense T1 lesions by using in vivo proton magnetic resonance spectroscopy, and analyzed the spectroscopic correlate of increased T1-relaxation time measurements. Localized proton magnetic resonance spectroscopy and T1-relaxation time measurements were performed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced MRI Techniques and Applications
Share to Multiple Sclerosis Research Studies
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10401783
DOI: 10.1002/1531-8249(199907)46:1<79::aid-ana12>3.0.co;2-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuronal damage in T1-hypointense multiple sclerosis lesions demonstrated in vivo using proton magnetic resonance spectroscopyPMID 10401783Read ↗

Disease-modifying therapies for T1 hypointense lesions (Black Holes) volume in patients with multiple sclerosis: Protocol for a systematic review and meta-analysisSemantic proximity Read ↗

In vivo evidence of differential frontal cortex metabolic abnormalities in progressive and relapsing‐remitting multiple sclerosisSemantic proximity Read ↗

Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation.Semantic proximity Read ↗

Altered Glutamate Homeostasis in Paramagnetic Rim Lesions of Patients with Multiple SclerosisSemantic proximity Read ↗

MPRAGE-derived quantitative T <sub>1</sub> mapping to assess diffuse white matter alterations in multiple sclerosisSemantic proximity Read ↗

Short T1 Fraction as a Marker of Myelin Content: Evidence from Postmortem MRI and HistologySemantic proximity Read ↗

Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes.Semantic proximity Read ↗

Can imaging techniques measure neuroprotection and remyelination in multiple sclerosis?Semantic proximity Read ↗

MR spectroscopic imaging of normal-appearing white matter in adrenoleukodystrophy.Semantic proximity Read ↗

Neuronal loss is an early component of subacute sclerosing panencephalitis.Semantic proximity Read ↗

1H-MR spectroscopy metabolite levels correlate with executive function in vascular cognitive impairmentSemantic proximity Read ↗

Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.