Article
Proton MR spectroscopic imaging predicts lesion progression on MRI in X-linked adrenoleukodystrophy.
Neurology - 26 Mar 2002
Eichler F S, Barker P B, Cox C, Edwin D, Ulug A M, Moser H W, Raymond G V
Abstract excerpt
BACKGROUND: The phenotypic expression of X-linked adrenoleukodystrophy (X-ALD) ranges from the rapidly progressive childhood cerebral form to the milder adrenomyeloneuropathy in adults. It is not possible to predict phenotype by mutation analysis or biochemical assays. Multislice proton MRS imaging (MRSI) has previously detected more extensive brain abnormalities in X-ALD than conventional MRI, which has been...
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