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Article

N-acetyltransferase 2 influences cancer prevalence in hMLH1/hMSH2 mutation carriers.

Cancer research - 1 Jul 1999

Heinimann K, Scott R J, Chappuis P, Weber W, Müller H, Dobbie Z, Hutter P

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC), an inherited cancer predisposition syndrome, has been associated with germline mutations in DNA mismatch repair (MMR) genes. Because a deficiency in MMR does not predict a specific cancer phenotype, modifying genes may account in part for the variation in disease expression. We determined the N-acetyltransferase 2 (NAT2) genotype in 26 unaffected and 52...

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Share to Adaptor Proteins, Signal Transducing
Share to Arylamine N-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Source

Identifiers

PMID: 10397239

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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N-acetyltransferase 2 influences cancer prevalence in hMLH1/hMSH2 mutation carriers.PMID 10397239Read ↗

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