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Article

Heat-shock and stringent responses have overlapping protease activity in Escherichia coli. Implications for heterologous protein yield.

Applied biochemistry and biotechnology - 1 Apr 1999

Harcum S W, Bentley W E

Abstract excerpt

The cellular response of a heat-shocked controlled chemostat of Escherichia coli JM105 [pSH101] was characterized and compared to that of a similar culture induced by isopropyl-beta-D-thiogalactopyranoside (IPTG). The proteases elicited by the IPTG pulse were previously shown to be upregulated by the stringent stress response and were shown here to be upregulated by heat shock, although to a lesser extent. Owing...

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PMID: 10394618
DOI: 10.1385/abab:80:1:23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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