Article
A cya deletion mutant of Escherichia coli develops thermotolerance but does not exhibit a heat-shock response.
Genetical research - 1 Feb 1990
Delaney J M
Abstract excerpt
An adenyl cyclase deletion mutant (cya) of E. coli failed to exhibit a heat-shock response even after 30 min at 42 degrees C. Under these conditions, heat-shock protein synthesis was induced by 10 min in the wild-type strain. These results suggest that synthesis of heat-shock proteins in E. coli requires the cya gene. This hypothesis is supported by the finding that a presumptive cyclic AMP receptor protein (CRP)...
Topics
- Adenylyl Cyclases
- Base Sequence
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Heat-Shock Proteins
- Molecular Sequence Data
- Mutation
- Temperature