Article
Genetic analysis of sorted Hodgkin and Reed-Sternberg cells using comparative genomic hybridization.
International journal of cancer - 19 Jul 1999
Ohshima K, Ishiguro M, Ohgami A, Sugihara M, Haraoka S, Suzumiya J, Kikuchi M
Abstract excerpt
Hodgkin and Reed-Sternberg (H and RS) cells are generally considered to be the neoplastic cells of Hodgkin's disease (HD); however, such cells are found only in a minority of HD lesions. Very few data have so far been published on the cytogenetic abnormalities in HD. An analysis of unknown genetic aberrations has only recently become possible through the use of comparative genomic hybridization (CGH), which is...
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