Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa.

doi:10.1128/JB.181.13.3890-3897.1999

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Article

Effect of rpoS mutation on the stress response and expression of virulence factors in Pseudomonas aeruginosa.

Journal of bacteriology - 1 Jul 1999

Suh S J, Silo-Suh L, Woods D E, Hassett D J, West S E, Ohman D E

Abstract excerpt

The sigma factor RpoS (sigmaS) has been described as a general stress response regulator that controls the expression of genes which confer increased resistance to various stresses in some gram-negative bacteria. To elucidate the role of RpoS in Pseudomonas aeruginosa physiology and pathogenesis, we constructed rpoS mutants in several strains of P. aeruginosa, including PAO1. The PAO1 rpoS mutant was subjected to...

Topics

Alginates
Animals
Bacterial Proteins
Heat-Shock Response
Lung Diseases
Mutation
Osmotic Pressure
Oxidants
Pseudomonas Infections
Pseudomonas aeruginosa
Rats
Sigma Factor

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Identifiers

PMID: 10383954
DOI: 10.1128/JB.181.13.3890-3897.1999
PMCID: PMC93876

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