Article
Presenilins in their infancy.
Chemistry & biology - 1 Jul 1999
Schweisguth F
Abstract excerpt
Familial forms of Alzheimer's disease are caused by mutations in the genes encoding the presenilins, which are integral membrane proteins. Presenilins have been shown to interact with beta-amyloid precursor proteins and Notch receptors. Several recent studies have examined the role of presenilins in Notch processing.
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