Development of animal models to study aggressive thyroid cancers.

Abstract excerpt

The development of mouse models for thyroid cancer has significantly advanced over the years, enhancing our understanding of thyroid tumorigenesis, molecular pathways and treatment responses. The earliest mouse models of thyroid cancer relied on hormone, radiation or chemical carcinogenesis to induce tumors. However, as our understanding of the genetic alterations driving thyroid cancer has expanded, more...

Topics

• Animals
• Thyroid Neoplasms
• Disease Models, Animal
• Mice
• Humans
• Mutation
• Disease Progression