Article
Oncogenic potential of Hsp72.
Oncogene - 17 Jun 1999
Volloch V Z, Sherman M Y
Abstract excerpt
Hsp72 is the major heat shock-inducible protein capable of protecting cells from a variety of stresses. In non-transformed cells at normal conditions Hsp72 is expressed at very low levels. It is, however, present at elevated levels in the major fraction of tumors and in many transformed cell lines. It is commonly assumed that in tumor cells the expression of Hsp72 at elevated levels is the consequence of...
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