Constitutive overexpression of the major inducible 70 kDa heat shock protein mediates large plaque formation by measles virus.

doi:10.1099/0022-1317-79-9-2239

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Article

Constitutive overexpression of the major inducible 70 kDa heat shock protein mediates large plaque formation by measles virus.

The Journal of general virology - 1 Sept 1998

Vasconcelos D Y, Cai X H, Oglesbee M J

Abstract excerpt

Induction of the cellular stress response elevates cytoplasmic levels of heat shock proteins (HSPs) belonging to multiple families. When infected with canine distemper virus or measles virus (MV), cells containing elevated HSPs support increased viral gene expression and cytopathic effect. The pr...

Topics

Animals
Clone Cells
Cytopathogenic Effect, Viral
Distemper Virus, Canine
Dogs
Gene Expression
Genes, Viral
HSP72 Heat-Shock Proteins
Heat-Shock Proteins
Humans
Measles virus
Nucleocapsid
Phenotype
Transfection
Viral Plaque Assay
Virulence

Source

Open in PubMed

Identifiers

PMID: 9747734
DOI: 10.1099/0022-1317-79-9-2239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9747734-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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