Article
Constitutive overexpression of the major inducible 70 kDa heat shock protein mediates large plaque formation by measles virus.
The Journal of general virology - 1 Sept 1998
Vasconcelos D Y, Cai X H, Oglesbee M J
Abstract excerpt
Induction of the cellular stress response elevates cytoplasmic levels of heat shock proteins (HSPs) belonging to multiple families. When infected with canine distemper virus or measles virus (MV), cells containing elevated HSPs support increased viral gene expression and cytopathic effect. The present work tests the hypothesis that increases in the major inducible 70 kDa HSP (hsp72) are sufficient to mediate the...
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