Article
GSTM1 polymorphism and lung cancer risk among East Asian populations: a meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014
Zhao Yan, Zeng Junjie, Zhang Yanxi, Lu Su, Zhao Erjiang, Huang Ziming, Lu Weiquan
Abstract excerpt
GSTM1 gene encodes a key enzyme involved in the metabolism of xenobiotics, and its polymorphisms have been related to individual susceptibility to several malignancies. Many molecular epidemiological studies were performed to investigate the association between the GSTM1 null polymorphism and lung cancer susceptibility in East Asia. However, the results were inconsistent. In order to derive a more precise...
Topics
- Asian People
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Glutathione Transferase
- Humans
- Lung Neoplasms
- Polymorphism, Single Nucleotide
- Risk Factors
