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Article

Brefeldin A inhibited activity of the sec7 domain of p200, a mammalian guanine nucleotide-exchange protein for ADP-ribosylation factors.

The Journal of biological chemistry - 18 Jun 1999

Morinaga N, Adamik R, Moss J, Vaughan M

Abstract excerpt

A brefeldin A (BFA)-inhibited guanine nucleotide-exchange protein (GEP) for ADP-ribosylation factors (ARF) was purified earlier from bovine brain cytosol. Cloning and expression of the cDNA confirmed that the recombinant protein (p200) is a BFA-sensitive ARF GEP. p200 contains a domain that is 50...

Topics

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ADP-Ribosylation Factor 1
ADP-Ribosylation Factors
Brefeldin A
GTP-Binding Proteins
Guanine Nucleotide Exchange Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Guanosine 5'-O-(3-Thiotriphosphate)

Phosphatidylserines

Source

Identifiers

PMID: 10364170
DOI: 10.1074/jbc.274.25.17417

Genes

ARF1
ARF5
ARF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10364170-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Brefeldin A inhibited activity of the sec7 domain of p200, a mammalian guanine nucleotide-exchange protein for ADP-ribosylation factors.PMID 10364170Read ↗

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