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Article

The influence of the p53 gene on the in vitro chemosensitivity of colorectal cancer cells.

Journal of cancer research and clinical oncology - 1 Jan 1999

Zheng M, Wang H, Zhang H, Ou Q, Shen B, Li N, Yu B

Abstract excerpt

PURPOSE: The p53 gene is considered one of the most important in the control of apoptosis, and its mutations have a close relationship with chemosensitivity. The aim of this work was to investigate the role of p53 in the apoptosis of colorectal cancer cells in vitro, induced by 5-fluorouracil (5-FU) and hydroxy-camptothecin (HCPT). METHODS: A total of 39 colorectal cancer samples from patients were treated in...

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Source

Identifiers

PMID: 10363568
DOI: 10.1007/s004320050286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The influence of the p53 gene on the in vitro chemosensitivity of colorectal cancer cells.PMID 10363568Read ↗

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