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Article

STAT protein recruitment and activation in c-Kit deletion mutants.

The Journal of biological chemistry - 11 Jun 1999

Brizzi M F, Dentelli P, Rosso A, Yarden Y, Pegoraro L

Abstract excerpt

Stem cell factor (SCF) and its tyrosine kinase receptor, c-Kit, play a crucial role in regulating migration and proliferation of melanoblasts, germ cells, and hemopoietic cell progenitors by activating a number of intracellular signaling molecules. Here we report that SCF stimulation of myeloid cells or fibroblasts ectopically expressing c-Kit induces physical association with and tyrosine phosphorylation of...

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Source

Identifiers

PMID: 10358045
DOI: 10.1074/jbc.274.24.16965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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