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Article

Semliki Forest virus mRNA capping enzyme requires association with anionic membrane phospholipids for activity.

The EMBO journal - 1 Jun 1999

Ahola T, Lampio A, Auvinen P, Kääriäinen L

Abstract excerpt

The replication complexes of all positive strand RNA viruses of eukaryotes are associated with membranes. In the case of Semliki Forest virus (SFV), the main determinant of membrane attachment seems to be the virus-encoded non-structural protein NSP1, the capping enzyme of the viral mRNAs, which has guanine-7-methyltransferase and guanylyltransferase activities. We show here that both enzymatic activities of SFV...

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Identifiers

PMID: 10357827
DOI: 10.1093/emboj/18.11.3164
PMCID: PMC1171397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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