Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A methionine aminopeptidase and putative regulator of translation initiation is required for cell growth and patterning in Drosophila.

Mechanisms of development - 1 Apr 1999

Cutforth T, Gaul U

Abstract excerpt

We have isolated mutations in the gene Drosophila methionine aminopeptidase 2 (DMAP2), which encodes a homolog of the type 2 methionine aminopeptidase from yeast, also known as the eukaryotic initiation factor 2alpha (eIF2alpha) associated protein p67. Weak DMAP2 mutations cause ommatidial rotation defects and loss of ventral tissue in the compound eye as well as extra wing veins, whereas stronger alleles impair...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aminopeptidases
Share to Body Patterning
Share to Drosophila Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Insect

Share to Glycoproteins

Share to Peptide Chain Initiation, Translational

Share to Wings, Animal

Source

Identifiers

PMID: 10354468
DOI: 10.1016/s0925-4773(99)00006-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A methionine aminopeptidase and putative regulator of translation initiation is required for cell growth and patterning in Drosophila.PMID 10354468Read ↗

A genetic screen for maternal-effect suppressors of decapentaplegic identifies the eukaryotic translation initiation factor 4A in Drosophila.Semantic proximity Read ↗

Cell-autonomous and non-autonomous growth-defective mutants of Drosophila melanogaster.Semantic proximity Read ↗

Adenylate kinase isozyme 2 is essential for growth and development of Drosophila melanogaster.Semantic proximity Read ↗

Genetic modifiers of dFMR1 encode RNA granule components in Drosophila.Semantic proximity Read ↗

The Drosophila Par domain protein I gene, Pdp1, is a regulator of larval growth, mitosis and endoreplication.Semantic proximity Read ↗

Mutations at the Ser50 residue of translation factor eIF-2alpha dominantly affect developmental rate, body weight, and viability of Drosophila melanogaster.Semantic proximity Read ↗

Disruption of Methionine Metabolism in Drosophila melanogaster Impacts Histone Methylation and Results in Loss of Viability.Semantic proximity Read ↗

4E-BP is a target of the GCN2-ATF4 pathway during Drosophila development and aging.Semantic proximity Read ↗

Drosophila myc regulates cellular growth during development.Semantic proximity Read ↗

Cell proliferation and DNA replication defects in a Drosophila MCM2 mutant.Semantic proximity Read ↗

The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4-driven growth.Semantic proximity Read ↗

Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.