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Article

Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development.

Genetics - 1 Jun 1999

Wharton K A, Cook J M, Torres-Schumann S, de Castro K, Borod E, Phillips D A

Abstract excerpt

We have isolated mutations in the Drosophila melanogaster gene glass bottom boat (gbb), which encodes a TGF-beta signaling molecule (formerly referred to as 60A) with highest sequence similarity to members of the bone morphogenetic protein (BMP) subgroup including vertebrate BMPs 5-8. Genetic analysis of both null and hypomorphic gbb alleles indicates that the gene is required in many developmental processes,...

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Source

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Identifiers

PMID: 10353905
DOI: 10.1093/genetics/152.2.629
PMCID: PMC1460618

Genes

BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic analysis of the bone morphogenetic protein-related gene, gbb, identifies multiple requirements during Drosophila development.PMID 10353905Read ↗

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A large bioactive BMP ligand with distinct signaling properties is produced by alternative proconvertase processing.Semantic proximity Read ↗

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