Article
Siglec-8 in induced sputum of COPD patients.
Advances in experimental medicine and biology - 1 Jan 2013
Mroz R M, Holownia A, Wielgat P, Sitko A, Skopinski T, Chyczewska E, Braszko J J
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is related to infiltration and activation of inflammatory cells in airways and pulmonary tissue. In COPD, neutrophils are prominent, while eosinophilic influx is typical to asthma. Inflammatory cells express sialic acid-binding immunoglobulin like lectins called Siglecs, a family of innate immune receptors that are transmembrane I-type lectins binding sialic acid. One...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
