Article
Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T lymphocytes.
The Journal of experimental medicine - 20 Jan 1997
Liu Y, Wenger R H, Zhao M, Nielsen P J
Abstract excerpt
A successful T cell immune response has two major products: effector T cells which directly or indirectly remove the antigens, and memory T cells, which allow a faster and more efficient recall response when challenged by related antigens. An important issue is whether costimulatory molecules on the antigen-presenting cells are involved in determining whether T cells will differentiate into effector or memory...
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