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Article

Cd(II)-responsive and constitutive mutants implicate a novel domain in MerR.

Journal of bacteriology - 1 Jun 1999

Caguiat J J, Watson A L, Summers A O

Abstract excerpt

Expression of the Tn21 mercury resistance (mer) operon is controlled by a metal-sensing repressor-activator, MerR. When present, MerR always binds to the same position on the DNA (the operator merO), repressing transcription of the structural genes merTPCAD in the absence of Hg(II) and inducing their transcription in the presence of Hg(II). Although it has two potential binding sites, the purified MerR homodimer...

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Identifiers

PMID: 10348859
DOI: 10.1128/JB.181.11.3462-3471.1999
PMCID: PMC93814

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Cd(II)-responsive and constitutive mutants implicate a novel domain in MerR.PMID 10348859Read ↗

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