Article
Cytogenetic analysis and RAS mutations in primary myelodysplastic syndromes.
Cancer genetics and cytogenetics - 1 Jun 1999
Plata E, Viniou N, Abazis D, Konstantopoulos K, Troungos C, Vaiopoulos G, Meletis J, Kittas C, Pangalos C, Yataganas X
Abstract excerpt
Cytogenetic analysis was performed in 60 patients with primary myelodysplastic syndromes--diagnosed, treated, and followed in our department. In 41 cases, the presence of the NRAS mutation was also evaluated. The aim of this study was to evaluate the prognostic value of chromosomal abnormalities and NRAS mutation. The median age of the patients was 67 years (18-88 years), and the French-American-British...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Anemia, Refractory
- Chromosome Aberrations
- Female
- Genes, ras
- Humans
- Karyotyping
- Leukemia, Myelomonocytic, Chronic
- Male
- Middle Aged
- Mutation
- Myelodysplastic Syndromes