Article
Cytogenetic studies, ras mutation, and clinical characteristics in primary myelodysplastic syndrome. A study on 68 Chinese patients in Taiwan.
Cancer genetics and cytogenetics - 1 May 1994
Tien H F, Wang C H, Chuang S M, Chow J M, Lee F Y, Liu M C, Chen Y C, Shen M C, Lin D T, Lin K H
Abstract excerpt
Cytogenetics and clinical features were studied for 68 Chinese patients with primary myelodysplastic syndrome (MDS). Ras mutation was analyzed in 25 of them. Thirty-four patients (50%) had clonal chromosomal abnormalities at initial analysis. The most common cytogenetic aberrations were -7, +8, 5...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Cell Transformation, Neoplastic
- Child
- Chromosome Aberrations
- Female
- Genes, ras
- Humans
- Immunoblotting
- Karyotyping
- Leukemia
- Male
- Middle Aged
- Mutation