Article
Association of oestrogen receptor gene polymorphisms with age at onset of rheumatoid arthritis.
Annals of the rheumatic diseases - 1 Jan 1999
Ushiyama T, Mori K, Inoue K, Huang J, Nishioka J, Hukuda S
Abstract excerpt
OBJECTIVE: In view of the possible role of oestrogens in the pathogenesis of rheumatoid arthritis (RA), this study investigated the association between oestrogen receptor (OR) gene polymorphisms and RA. METHODS: Pvu II and Xba I restriction fragment length polymorphisms of the OR gene were analysed in 70 male and 240 female patients with RA, and in 300 male and 350 female controls. The absence or presence of...
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