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Article

Genetic events and the role of TGFβ in epithelial tumour progression

1 Jan 1999

Abstract excerpt

The mouse skin model of chemical carcinogenesis has been very well characterized with respect to epigenetic changes, which occur during tumour cell initiation, promotion and progression. The use of transgenic and gene knock-out mice has contributed greatly to knowledge in this area. The H-ras genetic locus has been shown to undergo multiple genetic changes, including mutagenic activation, amplification of the...

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Identifiers

PMID: 10341708
DOI: 10.1002/(sici)1096-9896(199901)187:1<82::aid-path248>3.0.co;2-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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