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Article

On the experimental design and data analysis of mutation accumulation experiments.

Genetical research - 1 Apr 1999

Deng H W, Li J, Li J L

Abstract excerpt

Characterizing deleterious genomic mutations is important. Most of the few current estimates come from the mutation-accumulation (M-A) approach, which has been extremely time- and labour-consuming. There is a resurgent interest in implementing this approach. However, its estimation properties under different experimental designs are poorly understood. By simulations we investigate these issues in detail. We found...

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Identifiers

PMID: 10341667
DOI: 10.1017/s0016672398003681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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