Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The SRm160/300 splicing coactivator is required for exon-enhancer function

25 May 1999

Abstract excerpt

Exonic splicing enhancer (ESE) sequences are important for the recognition of splice sites in pre-mRNA. These sequences are bound by specific serine-arginine (SR) repeat proteins that promote the assembly of splicing complexes at adjacent splice sites. We have recently identified a splicing "coactivator," SRm160/300, which contains SRm160 (the SR nuclear matrix protein of 160 kDa) and a 300-kDa nuclear matrix...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA and protein synthesis mechanisms
Share to RNA Research and Splicing
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10339552
DOI: 10.1073/pnas.96.11.6125

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The SRm160/300 splicing coactivator is required for exon-enhancer functionPMID 10339552Read ↗

Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C. elegans.Semantic proximity Read ↗

Interactions of SR45, an SR-like protein, with spliceosomal proteins and an intronic sequence: insights into regulated splicing.Semantic proximity Read ↗

SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome.Semantic proximity Read ↗

Arginine/serine repeats are sufficient to constitute a splicing activation domain.Semantic proximity Read ↗

SPF30 Is an Essential Human Splicing Factor Required for Assembly of the U4/U5/U6 Tri-small Nuclear Ribonucleoprotein into the SpliceosomeSemantic proximity Read ↗

XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265.Semantic proximity Read ↗

Angel Wing: a class of alternative splicing regulators in animalsSemantic proximity Read ↗

The role of U2AF35 and U2AF65 in enhancer-dependent splicing.Semantic proximity Read ↗

RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans.Semantic proximity Read ↗

Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity.Semantic proximity Read ↗

Nuclear mRNA binding proteins couple pre-mRNA splicing and post-splicing events.Semantic proximity Read ↗

atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.