Article
Lack of association between genetic variation in the beta3-adrenergic receptor gene and insulin resistance in patients with coronary heart disease.
Metabolism: clinical and experimental - 1 May 1999
Sheu W H, Lee W J, Yao Y E, Jeng C Y, Young M M, Chen Y T
Abstract excerpt
The beta-adrenergic system plays a critical role in regulating lipolysis and thermogenesis. Recent studies have suggested that a missense Trp64Arg mutation in the beta3-adrenergic receptor gene is involved in visceral obesity and insulin resistance. We investigated the effect of this mutation on insulin resistance in patients with angiographically documented coronary heart disease ([CHD]n = 137) and normal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
