Article
Lack of relationship between beta3-adrenergic receptor gene polymorphism and gestational diabetes mellitus in a Taiwanese population.
Metabolism: clinical and experimental - 1 Sept 2004
Tsai Po-Jung, Ho Su-Chen, Tsai Li-Ping, Lee Yu-Hsiang, Hsu Shih-Penn, Yang Su-Pan, Chu Chun-Hong, Yu Chun-Hsien
Abstract excerpt
The Trp64Arg polymorphism of beta(3)-adrenergic receptor (ADRB3) has been reported to be associated with insulin resistance and gestational diabetes mellitus (GDM). The objective of this study is to investigate whether the ADRB3 Arg variant confers susceptibility to GDM in a Taiwanese population. A total of 299 pregnant women (mean +/- SD, 31.1 +/- 4.2 years) was recruited. Two-hour, 75-g oral glucose tolerance...
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