Article
Association of a genetic variation in the beta 3-adrenergic receptor gene with coronary heart disease among Japanese.
Biochemical and biophysical research communications - 27 Mar 1997
Higashi K, Ishikawa T, Ito T, Yonemura A, Shige H, Nakamura H
Abstract excerpt
Mutation frequencies in the beta 3-adrenergic receptor gene were measured in 83 CAD patients and 107 controls (all Japanese nationals) and the mutation incidence in the two groups was compared. The relationship between characteristics of lipid and glucose metabolism and presence or absence of the mutation was examined in CAD patients. The frequency of this mutant allele in CAD patients was significantly higher...
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