Article
Positive selection for indel substitutions in the rodent sperm protein catsper1.
Molecular biology and evolution - 1 Sept 2005
Podlaha Ondrej, Webb David M, Tucker Priscilla K, Zhang Jianzhi
Abstract excerpt
Catsper1 is a voltage-gated calcium channel located in the plasma membrane of the sperm tail and is necessary for sperm motility and fertility in mice. We here examine the evolutionary pattern of Catsper1 from nine species of the rodent subfamily Murinae of family Muridae. We show that the rate of insertion/deletion (indel) substitutions in exon 1 of the gene is 4-15 times that in introns or neutral genomic...
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