Article
An enlarged subpopulation of T lymphocytes bearing two distinct gammadelta TCR in an HIV-positive patient.
International immunology - 1 Apr 1999
Taupin J L, Halary F, Déchanet J, Peyrat M A, Ragnaud J M, Bonneville M, Moreau J F
Abstract excerpt
Although T cell clone monospecificity is ensured by several allelic exclusion processes operating at either the genotypic or phenotypic levels, clones expressing two distinct alphabeta or gammadelta TCR have been described in several instances. Thus far, the origin of dual TCR-expressing cells and the homeostatic mechanisms controlling the size of this subset in the periphery remain poorly understood. In the...
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