Article
A yeast strain defective in oleic acid utilization has a mutation in the RML2 gene.
Biochimica et biophysica acta - 18 May 1999
Trotter P J, Hagerman R A, Voelker D R
Abstract excerpt
The molecular mechanisms of cellular long-chain fatty acid assimilation and its regulation remain unclear. In an attempt to identify essential mediators of these processes, we have isolated mutant strains of the yeast Saccharomyces cerevisiae unable to utilize oleic acid as sole carbon source, while retaining the ability to utilize acetate. These strains are then subjected to several secondary screening assays to...
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