Article
Polyclonal expansion of TCRBV2- and TCRBV6-bearing T cells in patients with Kawasaki disease.
Immunology - 1 Mar 1999
Yoshioka T, Matsutani T, Iwagami S, Toyosaki-Maeda T, Yutsudo T, Tsuruta Y, Suzuki H, Uemura S, Takeuchi T, Koike M, Suzuki R
Abstract excerpt
We examined T-cell receptor (TCR) usage, cytokine production and antibody responses to superantigens in patients with Kawasaki disease (KD) to facilitate a better understanding of the immunopathogenesis of KD. The mean percentage of VB2- or VB6. 5-bearing T cells in peripheral blood mononuclear cells (PBMC) of patients with acute-phase KD was significantly higher than that of patients in the convalescent phase of...
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