Article
Dietary caffeine as a probe agent for assessment of cytochrome P4501A2 activity in random urine samples.
British journal of clinical pharmacology - 1 Apr 1999
Nordmark A, Lundgren S, Cnattingius S, Rane A
Abstract excerpt
AIMS: To validate the use of randomly collected urine samples for assessment of cytochrome P4501A2 (CYP1A2) activity based on dietary caffeine (caffeine metabolic ratio, MRcaff ), and to relate the MRcaff to caffeine intake and smoking habits in a larger group of individuals. METHODS: Nineteen healthy volunteers were included in the validation study. Caffeine (100 mg) was ingested and a urine sample was collected...
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