Article
Yersinia pseudotuberculosis-induced calcium signaling in neutrophils is blocked by the virulence effector YopH.
Infection and immunity - 1 May 1999
Andersson K, Magnusson K E, Majeed M, Stendahl O, Fällman M
Abstract excerpt
Pathogenic species of the genus Yersinia evade the bactericidal functions of phagocytes. This evasion is mediated through their virulence effectors, Yops, which act within target cells. In this study we investigated the effect of Yersinia pseudotuberculosis on Ca2+ signaling in polymorphonuclear neutrophils. The intracellular free calcium concentration in single adherent human neutrophils was monitored during...
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