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Article

Localization of the Yersinia PTPase to focal complexes is an important virulence mechanism.

Molecular microbiology - 1 Aug 1999

Persson C, Nordfelth R, Andersson K, Forsberg A, Wolf-Watz H, Fällman M

Abstract excerpt

The protein tyrosine phosphatase YopH, produced by the pathogen Yersinia pseudotuberculosis, is an essential virulence determinant involved in antiphagocytosis. Upon infection, YopH is translocated into the target cell, where it recognizes focal complexes. Genetic analysis revealed that YopH harbours a region that is responsible for specific localization of this PTPase to focal complexes in HeLa cells and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10447891
DOI: 10.1046/j.1365-2958.1999.01529.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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