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Article

Balancing proliferation and apoptosis in vivo: the Goldilocks theory of E2F/DP action.

Biochimica et biophysica acta - 25 Mar 1999

Yamasaki L

Abstract excerpt

Stimulation of both proliferation and apoptosis by E2F-1 provides a mechanistic basis for how E2F-1 functions as an oncogene and a tumor suppressor in vivo. In each normal tissue, a precise balance of proliferation versus apoptosis must be maintained, and in many tissues this appears to be contro...

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Source

Identifiers

PMID: 10214348
DOI: 10.1016/s0304-419x(99)00003-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10214348-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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