Article
Heterogeneity of HLA-G gene transcription and protein expression in malignant melanoma biopsies.
Cancer research - 15 Apr 1999
Paul P, Cabestré F A, Le Gal F A, Khalil-Daher I, Le Danff C, Schmid M, Mercier S, Avril M F, Dausset J, Guillet J G, Carosella E D
Abstract excerpt
Nonclassical MHC class I HLA-G antigen expression is tissue specific and is thought to play a role in tolerance of the semiallogeneic fetus by the maternal immune system. Ectopic expression of HLA-G by tumor cells provides them with an additional mechanism of escape from immunosurveillance by host cytotoxic effector mechanisms. The aim of this study was to assess the expression of nonclassical HLA-G antigens in...
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