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Article

Apoptosis as the Mechanism of Neurodegeneration in Batten's Disease

1 Aug 1996

Abstract excerpt

Batten's disease is a genetic neurodegenerative disease of childhood. Its hallmarks are retinitis pigmentosa and neuronal degeneration. As some types of photoreceptor death in mice are mediated by apoptosis, we investigated whether apoptosis is responsible for retinal and neuronal degeneration in the late infantile and juvenile forms of Batten's disease. Using the terminal dUDP nick end-labeling (TUNEL) staining...

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Identifiers

PMID: 8764595
DOI: 10.1046/j.1471-4159.1996.67020677.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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