Article
Exclusion of the apoE gene in autosomal dominant retinitis pigmentosa.
Vision research - 1 Dec 1998
Souied E H, Benlian P, Rozet J M, Gerber S, Lagarde J P, Coscas G, Soubrane G, Duffier J L, Munnich A, Kaplan J
Abstract excerpt
Our purpose was to search for mutations in the apolipoprotein E (apoE) gene and to evaluate the role of apoE polymorphisms in the occurrence of autosomal dominant retinitis pigmentosa (ADRP). The ApoE gene coding sequence was analyzed in 51 unrelated patients affected with ADRP. A screening for mutations by SSCP and an analysis of the apoE polymorphisms were performed using PCR and restriction enzymatic...
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