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Article

The combination of heteroduplex analysis and protein truncation test for exact detection of the APC gene mutations.

Neoplasma - 1 Jan 1998

Tomka M, Kirchhoff T, Kulcsár L, Stevurková V, Zajac V

Abstract excerpt

Familial adenomatous polyposis (FAP) is usually associated with mutation in the adenomatous polyposis coli (APC) gene. To examine the occurrence of these mutations in the number of FAP suspected families from the whole Slovakia effectively, we have applied heteroduplex analysis (HDA) and protein truncation test (PTT) for the analyses of 2-5 base pair deletions and point mutations of the APC gene. In the analyzed...

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Source

Identifiers

PMID: 10210106

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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