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Article

Novel mutations in the APC gene and clinical features in Swedish patients with polyposis coli.

Anticancer research - 1 Jan 2000

Nordling M, Engwall Y, Wahlström J, Wiklund L, Eriksson M A, Gustavsson B, Fasth S, Larsson P A, Martinsson T

Abstract excerpt

The adenomatous polyposis coli (APC) gene was investigated in Swedish patients with familial adenomatous polyposis (FAP). A combination of analyses including single stranded conformation polymorphism (SSCP), heteroduplex (HD), protein truncation test (PTT) and direct sequencing was used to enable optimal mutation detection. Three novel mutations in the gene were identified, i.e. nt2644C- > T (giving an Arg876Stop...

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Identifiers

PMID: 9494520

Genes

APC
FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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