Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of APC exon 15 mutations in families suspected of familial adenomatous polyposis (FAP).

Folia biologica - 1 Jan 1997

Kirchhoff T, Zajac V, Krizan P, Repiská V, Stevurková V, Friedl W

Abstract excerpt

Patients with familial adenomatous polyposis coli (FAP) reveal numerous colorectal adenomas as well as benign and malignant extracolonic lesions. Adenomatous polyposis coli (APC) gene mutations are the crucial genetic defect in FAP. The APC mutation molecular analysis of 20 FAP families was performed using the novel and effective method of the heteroduplex analysis (HDA). All of these families were screened for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to APC gene
Share to Exons
Share to Genetic Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Mutation

Share to Nucleic Acid Heteroduplexes

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 9595262

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of APC exon 15 mutations in families suspected of familial adenomatous polyposis (FAP).PMID 9595262Read ↗

Characterization of APC exon 15 germ-line mutation in FAP family with severe phenotype showing extracolonic symptoms.Semantic proximity Read ↗

The combination of heteroduplex analysis and protein truncation test for exact detection of the APC gene mutations.Semantic proximity Read ↗

Analysis of germline mutations in the APC gene in familial adenomatous polyposis patients.Semantic proximity Read ↗

First genotype characterization of Argentinean FAP patients: identification of 14 novel APC mutations.Semantic proximity Read ↗

Investigation of APC mutations in a Turkish familial adenomatous polyposis family by heterodublex analysis.Semantic proximity Read ↗

The most frequent APC mutations among Slovak familial adenomatous polyposis patients. Adenomatous polyposis coli.Semantic proximity Read ↗

Novel mutations in the APC gene and clinical features in Swedish patients with polyposis coli.Semantic proximity Read ↗

Familial adenomatous polyposis coli: five novel mutations in exon 15 of the adenomatous polyposis coli (APC) gene in Italian patients. Mutations in brief no. 225. Online.Semantic proximity Read ↗

Mutation analysis of the APC gene in Taiwanese FAP families: low incidence of APC germline mutation in a distinct subgroup of FAP families.Semantic proximity Read ↗

The mutation spectrum of the APC gene in FAP patients from southern Italy: detection of known and four novel mutations.Semantic proximity Read ↗

Genetic testing for familial adenomatous polyposis.Semantic proximity Read ↗

Three novel mutations of APC gene in Chinese patients with familial adenomatous polyposis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.