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Article

Effect of human papillomavirus infection on the immune system and its role in the course of cervical cancer

29 May 2015

Abstract excerpt

Human papillomavirus (HPV) is widely known as a cause of cervical intraepithelial neoplasia (CIN) and cervical cancer. The mechanisms involved have been studied by numerous studies. The integration of the virus genome into the host cells results in the abnormal regulation of cell cycle control. HPV can also induce immune evasion of the infected cells, which enable the virus to be undetectable for long periods of...

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PMID: 26622540
DOI: 10.3892/ol.2015.3295

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