Article
DNA pooling and dense marker maps: a systematic search for genes for cognitive ability.
Neuroreport - 17 Mar 1999
Hill L, Craig I W, Asherson P, Ball D, Eley T, Ninomiya T, Fisher P J, Turic D, McGuffin P, Owen M J, Chorney K, Chorney M J, Benbow C P, Lubinski D, Thompson L A, Plomin R
Abstract excerpt
Pooling DNA from subjects within a group and comparing the pooled DNA across groups for a dense map of DNA markers offers a solution to the conundrum that linkage is systematic but not powerful whereas allelic association is powerful but not systematic. We used DNA pooling to screen 66 markers on chromosome 22 in original and replication samples of children of high general cognitive ability (g) and controls of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
